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Muscle Gene Therapy, Gebunden
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Muscle Gene Therapy, Gebunden - nouveau livre

2011, ISBN: 1617379816

Gene therapy offers many conceptual advantages to treat muscle diseases, especially various forms of muscular dystrophies; however, it faces a number of unique challenges, including the n… Plus…

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Gene therapy offers many conceptual advantages to treat muscle diseases, especially various forms of muscular dystrophies; however, it faces a number of unique challenges, including the n… Plus…

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Muscle Gene Therapy: Methods and Protocols (Methods in Molecular Biology, 709, Band 709)
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Muscle Gene Therapy: Methods and Protocols (Methods in Molecular Biology, 709, Band 709) - edition reliée, livre de poche

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ISBN: 9781617379819

Humana, Gebundene Ausgabe, Auflage: 2011, 395 Seiten, Publiziert: 2011-01-10T00:00:01Z, Produktgruppe: Buch, Hersteller-Nr.: 31523064, 2.07 kg, Medizin, Kategorien, Bücher, Immunologie, G… Plus…

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Dongsheng Duan:
Muscle Gene Therapy Methods and Protocols 709 Methods in Molecular Biology - Livres de poche

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Muscle Gene Therapy - edition reliée, livre de poche

2011, ISBN: 1617379816

[EAN: 9781617379819], Neubuch, [PU: Humana Press], Print on Demand pp. 398, Books

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Détails sur le livre
Muscle Gene Therapy: Methods and Protocols (Methods in Molecular Biology, 709, Band 709)
Auteur:
Titre:
ISBN:

1617379816


Gene therapy offers many conceptual advantages to treat muscle diseases, especially various forms of muscular dystrophies; however, it faces a number of unique challenges, including the need to deliver a therapeutic vector to all muscles throughout the body. In Muscle Gene Therapy: Methods and Protocols, expert researchers in the field present a collection of techniques aimed at bridging the translational gap in muscle gene therapy between the prevalent rodent models and vitally important larger animal models. Divided into three sections, this volume examines basic protocols for optimizing the muscle gene expression cassette and for evaluating the therapeutic outcomes, new developments in muscle gene therapy technology such as adeno-associated viral vector (AAV), oligonucleotide-mediated exon-skipping, and novel RNA-based strategies, and step-by-step guidance on muscle gene delivery in swine, ovine, canine, and non-human primates. Written in the highly successful Methods in Molecular Biology(TM) series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, detailed, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Authoritative and cutting-edge, Muscle Gene Therapy: Methods and Protocols serves as an invaluable resource for graduate students, post-doctoral fellows, and principle investigators pursuing the crucial advancement of muscle disease gene therapy in the hope of someday curing these debilitating disorders.

Informations détaillées sur le livre - Muscle Gene Therapy: Methods and Protocols (Methods in Molecular Biology, 709, Band 709)


EAN (ISBN-13): 9781617379819
ISBN (ISBN-10): 1617379816
Version reliée
Livre de poche
Date de parution: 2011
Editeur: Duan, Dongsheng, Humana
382 Pages
Poids: 0,881 kg
Langue: eng/Englisch

Livre dans la base de données depuis 2008-05-31T18:19:31+02:00 (Zurich)
Page de détail modifiée en dernier sur 2023-09-27T12:52:10+02:00 (Zurich)
ISBN/EAN: 1617379816

ISBN - Autres types d'écriture:
1-61737-981-6, 978-1-61737-981-9
Autres types d'écriture et termes associés:
Auteur du livre: duan
Titre du livre: therapy, molecular biology the gene, muscle

Données de l'éditeur

Auteur: Dongsheng Duan
Titre: Methods in Molecular Biology; Muscle Gene Therapy - Methods and Protocols
Editeur: Humana; Humana Press
382 Pages
Date de parution: 2011-01-10
Totowa; NJ; US
Imprimé / Fabriqué en
Langue: Anglais
106,99 € (DE)
109,99 € (AT)
118,00 CHF (CH)
POD
XIII, 382 p.

BB; Hardcover, Softcover / Medizin/Klinische Fächer; Genetik, Medizin; Verstehen; AAV; Adeno-associated viral vectors; Delivery systems; Exon-skipping; Gene expression cassette; Gene mutations; Large animal models; Muscular degeneration; gene therapy; Medical Genetics; Genetics and Genomics; Clinical Genetics; Genetik (nicht-medizinisch); EA; BC

Gene therapy offers many conceptual advantages to treat muscle diseases, especially various forms of muscular dystrophies; however, it faces a number of unique challenges, including the need to deliver a therapeutic vector to all muscles throughout the body. In Muscle Gene Therapy: Methods and Protocols, expert researchers in the field present a collection of techniques aimed at bridging the translational gap in muscle gene therapy between the prevalent rodent models and vitally important larger animal models. Divided into three sections, this volume examines basic protocols for optimizing the muscle gene expression cassette and for evaluating the therapeutic outcomes, new developments in muscle gene therapy technology such as adeno-associated viral vector (AAV), oligonucleotide-mediated exon-skipping, and novel RNA-based strategies, and step-by-step guidance on muscle gene delivery in swine, ovine, canine, and non-human primates. Written in the highly successful Methods in Molecular Biology™ series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, detailed, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Muscle Gene Therapy: Methods and Protocols serves as an invaluable resource for graduate students, post-doctoral fellows, and principle investigators pursuing the crucial advancement of muscle disease gene therapy in the hope of someday curing these debilitating disorders.
Presents a comprehensive collection of state-of-the-art muscle gene therapy protocols from leaders in the field Focuses on gene delivery in less-covered large animal models, such as swine, ovine, canine, and non-human primates Contains tips from the experts highlighting key implementation advice and strategies Includes supplementary material: sn.pub/extras
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