2012, ISBN: 9783527330157
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2012, ISBN: 9783527330157
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Series Editor: Mannhold, Raimund, Series Editor: Kubinyi, Hugo, Series Editor: Folkers, Gerd, Wiley-VCH, Gebundene Ausgabe, Auflage: 1. 256 Seiten, Publiziert: 2012-08-22T00:00:01Z, Produ… Plus…
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2012, ISBN: 3527330151
[EAN: 9783527330157], Neubuch, [PU: Wiley-VCH], Books
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2012, ISBN: 9783527330157
Gebunden, 256 Seiten, 250mm x 175mm x 18mm, Sprache(n): eng Written with the practicing medicinal chemist in mind, this is the first modern handbook to systematically address the topic of… Plus…
2012, ISBN: 9783527330157
Edition reliée
Series Editor: Mannhold, Raimund, Series Editor: Kubinyi, Hugo, Series Editor: Folkers, Gerd, Wiley-VCH, Gebundene Ausgabe, Auflage: 1. 256 Seiten, Publiziert: 2012-08-22T00:00:01Z, Produ… Plus…
ISBN: 9783527330157
*Bioisosteres in Medicinal Chem* - 1. Auflage / gebundene Ausgabe für 211.49 € / Aus dem Bereich: Bücher, Wissenschaft, Chemie Medien > Bücher nein Buch (gebunden) Hardcover;Naturwissensc… Plus…
2012, ISBN: 3527330151
[EAN: 9783527330157], Neubuch, [PU: Wiley-VCH], Books
ISBN: 9783527330157
hardback, [PU: Wiley-VCH, Weinheim]
Données bibliographiques du meilleur livre correspondant
Auteur: | |
Titre: | |
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As such, it provides a ready reference on the principles and methods of bioisosteric replacement as a key tool in preclinical drug development.
The first part provides an overview of bioisosterism, classical bioisosteres and typical molecular interactions that need to be considered,
while the second part describes a number of molecular databases as sources of bioisosteric identification and rationalization. The third part
covers the four key methodologies for bioisostere identification and replacement: physicochemical properties, topology, shape, and overlays of
protein-ligand crystal structures. In the final part, several real-world examples of bioisosterism in drug discovery projects are discussed.
With its detailed descriptions of databases, methods and real-life case studies, this is tailor-made for busy industrial researchers with little time for reading, while remaining easily accessible to novice drug developers due to its systematic structure and introductory section.
Informations détaillées sur le livre - Bioisosteres in Medicinal Chemistry (Methods and Principles in Medicinal Chemistry, 54, Band 54)
EAN (ISBN-13): 9783527330157
ISBN (ISBN-10): 3527330151
Version reliée
Livre de poche
Date de parution: 2012
Editeur: Brown, Nathan, Wiley-VCH
237 Pages
Poids: 0,638 kg
Langue: Englisch
Livre dans la base de données depuis 2008-03-08T07:09:28+01:00 (Zurich)
Page de détail modifiée en dernier sur 2023-12-19T23:57:51+01:00 (Zurich)
ISBN/EAN: 3527330151
ISBN - Autres types d'écriture:
3-527-33015-1, 978-3-527-33015-7
Autres types d'écriture et termes associés:
Auteur du livre: nath, nathan brown, wiley vch verlag gmbh, hugo kubinyi, gerd folkers
Titre du livre: hugo, brown, principles chemistry, chem
Données de l'éditeur
Auteur: Nathan Brown
Titre: Methods and Principles in Medicinal Chemistry; Bioisosteres in Medicinal Chemistry
Editeur: Wiley-VCH; Wiley-VCH
238 Pages
Date de parution: 2012-08-22
Imprimé / Fabriqué en
Poids: 0,624 kg
Langue: Anglais
162,00 € (DE)
166,60 € (AT)
Available
170mm x 240mm x 16mm
BB; Hardcover, Softcover / Chemie; Medizinische Chemie, Pharmazeutische Chemie; Verstehen; Biochemie u. Chemische Biologie; Biochemistry (Chemical Biology); Chemie; Chemistry; Computational Chemistry & Molecular Modeling; Computational Chemistry u. Molecular Modeling; Drug Discovery & Development; Medizinische Chemie; Wirkstoffforschung; Wirkstoffforschung u. -entwicklung; Wirkstoffforschung u. -entwicklung; Biochemie u. Chemische Biologie; Computational Chemistry u. Molecular Modeling
Written with the practicing medicinal chemist in mind, this is the first modern handbook to systematically address the topic of bioisosterism. As such, it provides a ready reference on the principles and methods of bioisosteric replacement as a key tool in preclinical drug development. The first part provides an overview of bioisosterism, classical bioisosteres and typical molecular interactions that need to be considered, while the second part describes a number of molecular databases as sources of bioisosteric identification and rationalization. The third part covers the four key methodologies for bioisostere identification and replacement: physicochemical properties, topology, shape, and overlays of protein-ligand crystal structures. In the final part, several real-world examples of bioisosterism in drug discovery projects are discussed. With its detailed descriptions of databases, methods and real-life case studies, this is tailor-made for busy industrial researchers with little time for reading, while remaining easily accessible to novice drug developers due to its systematic structure and introductory section.Autres livres qui pourraient ressembler au livre recherché:
Dernier livre similaire:
9783527654321 Bioisosteres in Medicinal Chemistry (Gerd Folkers, Hugo Kubinyi, Nathan Brown, Raimund Mannhold)
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