ISBN: 9780387768427
Human immunosenescence contributes to morbidity and mortality in later life. The age-associated increasing incidence of cancer and cardiovascular disease plateaus at around 80 years of ag… Plus…
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2008, ISBN: 9780387768427
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ISBN: 9780387768427
Human immunosenescence contributes to morbidity and mortality in later life. The age-associated increasing incidence of cancer and cardiovascular disease plateaus at around 80 years of ag… Plus…
2008, ISBN: 9780387768427
eBooks, eBook Download (PDF), 2007, Human immunosenescence contributes to morbidity and mortality in later life. The age-associated increasing incidence of cancer and cardiovascular disea… Plus…
2008
ISBN: 9780387768427
eBooks, eBook Download (PDF), Auflage, [PU: Springer-Verlag], Seiten: 194, Springer-Verlag, 2008
2008, ISBN: 9780387768427
eBooks, eBook Download (PDF), Auflage, [PU: Springer-Verlag], [ED: 1], Springer-Verlag, 2008
2008, ISBN: 9780387768427
eBooks, eBook Download (PDF), 2007, [PU: Springer New York], Springer New York, 2008
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Informations détaillées sur le livre - Immunosenescence
EAN (ISBN-13): 9780387768427
Date de parution: 2008
Editeur: Springer New York
194 Pages
Langue: eng/Englisch
Livre dans la base de données depuis 2008-11-08T11:36:56+01:00 (Zurich)
Page de détail modifiée en dernier sur 2024-03-16T12:19:37+01:00 (Zurich)
ISBN/EAN: 9780387768427
ISBN - Autres types d'écriture:
978-0-387-76842-7
Autres types d'écriture et termes associés:
Auteur du livre: pawelec, graham
Données de l'éditeur
Auteur: Graham Pawelec
Titre: Medical Intelligence Unit; Immunosenescence
Editeur: Springer; Springer US; Landes Bioscience
194 Pages
Date de parution: 2008-12-18
New York; NY; US
Langue: Anglais
149,79 € (DE)
154,00 € (AT)
177,00 CHF (CH)
Available
XVIII, 194 p. 46 illus., 5 illus. in color.
EA; E107; eBook; Nonbooks, PBS / Medizin/Nichtklinische Fächer; Medizinische Forschung; Verstehen; Immunosenescence; age; aging; assessment; autoimmune disease; cancer; infectious diseases; morbidity; senescence; C; Biomedicine, general; Biomedical Research; Biomedical and Life Sciences; BB
1. Immune Risk Phenotypes and Associated Parameters in Very Old Humans: A Review of Findings in the Swedish NONA Immune Longitudinal Study........................................................................................1 Anders Wikby, Frederick Ferguson, Jan Strindhall, Rosalyn J. Forsey, Tamas Fulop, Sine Reker Hadrup, Per thor Straten, Graham Pawelec and Boo Johansson Introduction................................................................................................................1 NONA Immune Subjects........................................................................................3 Health Parameters.....................................................................................................4 Immune System Parameters.....................................................................................4 Immune Parameters and Morbidity......................................................................4 Immune Risk Phenotype, Cognitive Impairment and Mortality..................5 Allostatic Load............................................................................................................6 IRP, T-Cell Differentiation and Persistent Viral Infection..............................7 TCR Clonotype Mapping......................................................................................10 Low Grade Inflammation......................................................................................11 IRP Movement..........................................................................................................11 Conclusions and Future Direction.......................................................................12 2. Scoring of Immunological Vigor: Trial Assessment of Immunological Status as a Whole for Elderly People and Cancer Patients....................................15 Katsuiku Hirokawa, Masanori Utsuyama, Yuko Kikuchi and Masanobu Kitagawa Infection Is a Major Cause of Death in the Elderly..........................................15 A Significant Number of Cancer Patients Die of Infection...........................16 Assessment of the Immunological State.............................................................18 Restoration of Immune Function........................................................................ 20 Effect of Infusing Activated T-Cells in the Mouse Model.............................21 3. Remodelling of the CD8 T-Cell Compartment in the Elderly: Expression of NK Associated Receptors on T-Cells Is Associated with the Expansion of the Effector Memory Subset....................................................................24 Inmaculada Gayoso, M Luisa Pita, Esther Peralbo, Corona Alonso, Olga DelaRosa, Javier G. Casado, Julian de la Torre-Cisneros, Raquel Tarazona and Rafael Solana Introduction............................................................................................................. 24 Expression of NKR on T-Cells in Ageing: The Expansion of CD8 T-Cells Expressing NK Associated Receptors in the Elderly Is due to the Expansion of Effector Memory 2 T-Lymphocytes.......................................25 CMV-Specific CD8 T-Cells Are Expanded in the Elderly Expression of NK Associated Receptors................................................................................. 28 Concluding Remarks and Future Prospects..................................................... 30 4. Telomeres, Telomerase and CD28 in Human CD8 T-cells: Effects on Immunity during aging and HIV infection..........................................34 Steven R. Fauce and Rita B. EffrAutres livres qui pourraient ressembler au livre recherché:
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