Space Pharmacology - nouveau livre

Livre dans la base de données depuis 2012-05-31T21:31:26+02:00 (Zurich)
Page de détail modifiée en dernier sur 2023-03-01T13:11:30+01:00 (Zurich)
ISBN/EAN: 9781461433965

ISBN - Autres types d'écriture:
1-4614-3396-7, 978-1-4614-3396-5
Autres types d'écriture et termes associés:
Auteur du livre: stephane groueff

Données de l'éditeur

Auteur: Virginia E. Wotring
Titre: SpringerBriefs in Space Development; Space Pharmacology
Editeur: Springer; Springer US
109 Pages
Date de parution: 2012-03-15
New York; NY; US
Imprimé / Fabriqué en
Langue: Anglais
64,19 € (DE)
66,00 € (AT)
71,00 CHF (CH)
Available
XI, 109 p. 23 illus., 9 illus. in color.

EA; E107; eBook; Nonbooks, PBS / Physik, Astronomie/Astronomie; Angewandte Physik; Verstehen; Long duration exploration missions; Manned space flight; Space flight environment; Space flight safety; Space medicine; Space pharmaceuticals; Space pharmacodynamics; Space pharmacokinetics; Space physiology; Space travel; C; Space Sciences (including Extraterrestrial Physics, Space Exploration and Astronautics); Pharmaceutical Sciences/Technology; Inorganic Chemistry; Space Physics; Pharmaceutics; Inorganic Chemistry; Physics and Astronomy; Sonnensystem: Sonne und Planeten; Medizinische Chemie, Pharmazeutische Chemie; Anorganische Chemie; BC

Chapter 1: Introduction.- Chapter 2: Absorption.- Chapter 3: Distribution.- Chapter 4: Metabolism and Excretion.- Chapter 5: Central Nervous System.- Chapter 6: Cardiovascular System.- Chapter 7: Gastrointestinal System.- Chapter 8: Musculoskeletal System.- Chapter 9: Multiple Systems Spaceflight Effects.- Chapter 10: Conclusions - Special Challenges of Long Duration Exploration.- References.- Abbreviations.

Dr. Virginia Wotring is a Senior Scientist in the Division of Space Life Sciences at Universities Space Research Association, and Pharmacology Discipline Lead at NASA's Johnson Space Center, Human Health and Countermeasures. She received her doctorate in Pharmacological and Physiological Sciences at Saint Louis University after earning a BS in Chemistry at Florida State University. She has extensive experience studying drug mechanisms of action, drug receptor structure/function relationships, and gene and protein expression.

In 2009, she began directing the NASA JSC Pharmacology Lab, whose mission is to ensure that medications used during spaceflight will act in a predictable, effective and safe manner. The spaceflight environment includes several unusual stressors for the body: microgravity, fluid shifting, increased radiation exposure, lack of circadian cues and others. Each of these can alter normal physiology, and thus, change the way in which drugs are absorbed, distributed, metabolized, excreted or how they interact with physiological targets. Current projects include: determining cardiac safety of new and experimental anti-motion sickness combination therapies, and measurement of gene and protein expression after exposure to spaceflight or a gamma radiation analog of spaceflight.

Dr. Wotring is also actively involved in mentoring students and interns, and participates in teaching at area universities. She holds adjunct appointments in the UTMB Galveston Department of Pharmacology and Toxicology and at the University of Houston's Department of Health and Human Performance.

Presents the practice and problems associated with the use of pharmaceuticals in the extreme environment of spaceflight