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Extensive research has uncovered a set of molecular surveillance mechanisms - commonly called "checkpoints" - which tightly monitor cell-cycle processes. Today''s anti… Plus…

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Extensive research has uncovered a set of molecular surveillance mechanisms - commonly called "checkpoints" - which tightly monitor cell-cycle processes. Today''s anticancer drug developm… Plus…

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2010

ISBN: 9781617378478

Extensive research has uncovered a set of molecular surveillance mechanisms – commonly called “checkpoints” – which tightly monitor cell-cycle proc… Plus…

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Checkpoint Responses in Cancer Therapy - nouveau livre

ISBN: 9781617378478

Extensive research has uncovered a set of molecular surveillance mechanisms - commonly called "checkpoints" - which tightly monitor cell-cycle processes. Today''s anticancer dru… Plus…

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ISBN: 9781617378478

Paperback, [PU: Humana Press Inc.], Checkpoint Responses in Cancer Therapy summarizes the advances made over the past 20 years, identifying components of cell-cycle checkpoints and their … Plus…

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Checkpoint Responses in Cancer Therapy by Wei Dai Paperback | Indigo Chapters

Extensive research has uncovered a set of molecular surveillance mechanisms - commonly called "checkpoints" - which tightly monitor cell-cycle processes. Today's anticancer drug development has identified many of these cell-cycle checkpoint molecules as effective targets. Research now promises to uncover a new generation of anticancer drugs with improved therapeutic indices based on their ability to target emerging checkpoint components. Checkpoint Responses in Cancer Therapy summarizes the advances made over the past 20 years, identifying components of cell-cycle checkpoints and their molecular regulation during checkpoint activation and validating the use of checkpoint proteins as targets for the development of anticancer drugs. This book's distinguished panel of authors takes a close look at topics ranging from the major molecular players affecting DNA synthesis and the response to DNA damage to advances made in the identification of chemical compounds capable of inhibiting individual mitotic kinases. Illuminating and authoritative, Checkpoint Responses in Cancer Therapy offers a critical summary of findings for researchers in the pharmaceutical and biotechnology industries and a valuable resource for academic scientists in cancer research and the study of cell-cycle regulation, signal transduction and apoptosis.

Informations détaillées sur le livre - Checkpoint Responses in Cancer Therapy by Wei Dai Paperback | Indigo Chapters


EAN (ISBN-13): 9781617378478
ISBN (ISBN-10): 161737847X
Livre de poche
Date de parution: 2010
Editeur: Wei Dai
328 Pages
Poids: 0,494 kg
Langue: eng/Englisch

Livre dans la base de données depuis 2012-03-14T22:55:53+01:00 (Zurich)
Page de détail modifiée en dernier sur 2022-10-07T19:29:45+02:00 (Zurich)
ISBN/EAN: 9781617378478

ISBN - Autres types d'écriture:
1-61737-847-X, 978-1-61737-847-8
Autres types d'écriture et termes associés:
Auteur du livre: wei
Titre du livre: checkpoint


Données de l'éditeur

Auteur: Wei Dai
Titre: Cancer Drug Discovery and Development; Checkpoint Responses in Cancer Therapy
Editeur: Humana; Humana Press
314 Pages
Date de parution: 2010-11-19
Totowa; NJ; US
Imprimé / Fabriqué en
Poids: 0,504 kg
Langue: Anglais
213,99 € (DE)
219,99 € (AT)
236,00 CHF (CH)
POD
XIV, 314 p. 33 illus., 3 illus. in color.

BC; Cancer Research; Hardcover, Softcover / Medizin/Nichtklinische Fächer; Onkologie; Verstehen; DNA; apoptosis; biotechnology; cancer; cancer research; cancer therapy; cell; cell cycle; checkpoint; chemotherapy; development; drug; drug design; drug development; research; Pharmacology/Toxicology; Cancer Biology; Pharmacology; Pharmakologie; BB

Preface Action of the RB pathway in response to therapeutic agents Erik S. Knudsen Targeting the p53/MDM2 pathway for cancer therapy Lyubomir T. Vassilev DNA topoisomerases as targets for the chemotherapeutic treatment of cancer Neil Osheroff Targeting the DNA damage checkpoint (ATM/ATR) Wafik S. El-Deiry (Not in yet) Compounds that abrogate the G2 checkpoint Takumi Kawabe CDK inhibitors as anti-cancer agents J. de Bono CHFR as a potential anti-cancer target T. Tokino Antimicrotubule agents M. Villalona-Calero Kinesin motor inhibitors as effective anti-cancer drugs A. Giannis Targeting the spindle checkpoint in cancer chemotherapy Hongtao Yu Anti-proliferation inhibitors targeting aurora kinases Daruka Mahadevan Plks as novel targets for cancer drug design Wei Dai Do histone deacetylase inhibitors target cell cycle checkpoints that monitor heterochromatin structure? Brian G. Gabrielli

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