2012, ISBN: 3527330852
[EAN: 9783527330850], Neubuch, [PU: Wiley-VCH GmbH], CHEMIE MEDIZIN BASIC PHARMACOLOGY CHEMISTRY DRUG DISCOVERY & DEVELOPMENT GRUNDLAGEN DER PHARMAKOLOGIE MEDICAL SCIENCE TOXICOLOGY TOXIK… Plus…
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Reactive Drug Metabolites (Methods and Principles in Medicinal Chemistry) - edition reliée, livre de poche
2012, ISBN: 9783527330850
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2012, ISBN: 9783527330850
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Reactive Drug Metabolites (Methods and Principles in Medicinal Chemistry) - edition reliée, livre de poche
2012, ISBN: 3527330852
[EAN: 9783527330850], Neubuch, [PU: Wiley VCH 2012-10-24]
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2012, ISBN: 9783527330850
Edition reliée
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2012, ISBN: 3527330852
[EAN: 9783527330850], Neubuch, [PU: Wiley-VCH GmbH], CHEMIE MEDIZIN BASIC PHARMACOLOGY CHEMISTRY DRUG DISCOVERY & DEVELOPMENT GRUNDLAGEN DER PHARMAKOLOGIE MEDICAL SCIENCE TOXICOLOGY TOXIK… Plus…
Kalgutkar, Amit S.; Dalvie, Deepak; Obach, R. Scott; Smith, Douglas A.; Mannhold, Raimund [Series Editor]; Kubinyi, Hugo [Series Editor]; Folkers, Gerd [Series Editor];:
Reactive Drug Metabolites (Methods and Principles in Medicinal Chemistry) - edition reliée, livre de poche2012, ISBN: 9783527330850
Wiley-VCH, 2012-12-26. Hardcover. Used:Good., Wiley-VCH, 2012-12-26, 0
Reactive Drug Metabolites (Methods and Principles in Medicinal Chemistry) - edition reliée, livre de poche
2012
ISBN: 9783527330850
Wiley-VCH, 2012-12-26. 1. Hardcover. Good., Wiley-VCH, 2012-12-26, 2.5
Reactive Drug Metabolites (Methods and Principles in Medicinal Chemistry) - edition reliée, livre de poche
2012, ISBN: 3527330852
[EAN: 9783527330850], Neubuch, [PU: Wiley VCH 2012-10-24]
2012, ISBN: 9783527330850
Edition reliée
Buch, Hardcover, 1. Auflage, [PU: Wiley-VCH], Wiley-VCH, 2012
Données bibliographiques du meilleur livre correspondant
Auteur: | |
Titre: | |
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pharmaceutical companies worldwide. The first chapters trace the development of our understanding of drug metabolite toxicity, covering basic concepts and techniques in the process, while the second part details chemical toxicophores that are prone to reactive metabolite formation. This section also reviews the various drug-metabolizing enzymes that can participate in catalyzing reactive metabolite formation, including a discussion of the structure-toxicity relationships for drugs. Two chapters are dedicated to the currently hot topics of herbal constituents and IADRs.
The next part covers current strategies and approaches to evaluate the reactive metabolite potential of new drug candidates, both by predictive
and by bioanalytical methods. There then follows an in-depth analysis of the toxicological potential of the top 200 prescription drugs, illustrating
the power and the limits of the toxicophore concept, backed by numerous case studies. Finally, a risk-benefi t approach to managing the toxicity risk of reactive metabolite-prone drugs is presented.
Since the authors carefully develop the knowledge needed, from fundamental considerations to current industry standards, no degree in pharmacology is required to read this book, making it perfect for medicinal chemists without in-depth pharmacology training.
Informations détaillées sur le livre - Reactive Drug Metabolites
EAN (ISBN-13): 9783527330850
ISBN (ISBN-10): 3527330852
Version reliée
Date de parution: 2012
Editeur: Wiley-VCH
386 Pages
Poids: 1,017 kg
Langue: Englisch
Livre dans la base de données depuis 2007-04-28T00:39:27+02:00 (Zurich)
Page de détail modifiée en dernier sur 2023-04-05T14:49:48+02:00 (Zurich)
ISBN/EAN: 9783527330850
ISBN - Autres types d'écriture:
3-527-33085-2, 978-3-527-33085-0
Autres types d'écriture et termes associés:
Auteur du livre: scott, deepak, amit, douglas smith, dennis, raimund, hugo kubinyi, gerd folkers, kalg
Titre du livre: amit
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9783527655762 Reactive Drug Metabolites (Amit S. Kalgutkar, Deepak Dalvie, R. Scott Obach, Dennis A. Smith)
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