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The Ubiquitin System in Health and Disease. Edited by S. Jentsch and B. Haendler. (Ernst Schering Foundation Symposium Proceedings 2008-1). - edition reliée, livre de poche

2009, ISBN: 9783540851066

Berlin, Heidelberg & New York, Springer, XV, 190 Seiten. Mit 39 Abbildungen. 8° (17,5-22,5 cm). Orig.-Pappband. [Hardcover / fest gebunden]. Neuwertiges Exemplar. / As new. ISBN: 97835408… Plus…

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The Ubiquitin System in Health and Disease

The ubiquitin system plays an essential role in numerous cellular processes by controlling protein stability and function. A deregulation of this system has been reported in various pathologies including cancer, neurodegenerative diseases and immune disorders. Most of the enzymes involved in adding or removing ubiquitin chains have been identified, but often their direct substrate and the type of ubiquitylation remains to be clarified. A better understanding of the mechanisms governing these processes is likely to allow the identification of novel targets for pharmacological intervention and pave the way for improved therapies. The latest developments in this rapidly moving field are presented in this book.

Informations détaillées sur le livre - The Ubiquitin System in Health and Disease


EAN (ISBN-13): 9783540851066
ISBN (ISBN-10): 3540851062
Version reliée
Date de parution: 2008
Editeur: Springer Berlin
191 Pages
Poids: 0,391 kg
Langue: eng/Englisch

Livre dans la base de données depuis 2007-05-17T11:51:04+02:00 (Zurich)
Page de détail modifiée en dernier sur 2024-03-03T02:11:09+01:00 (Zurich)
ISBN/EAN: 9783540851066

ISBN - Autres types d'écriture:
3-540-85106-2, 978-3-540-85106-6
Autres types d'écriture et termes associés:
Auteur du livre: händler, schering, haen, ernst jentsch, bernhard, haendler, place
Titre du livre: health disease, the ernst, system, the symposium, ernst schering research foundation workshop, jentsch


Données de l'éditeur

Auteur: Stefan Jentsch; Bernhard Haendler
Titre: Ernst Schering Foundation Symposium Proceedings; The Ubiquitin System in Health and Disease
Editeur: Springer; Springer Berlin
191 Pages
Date de parution: 2008-12-10
Berlin; Heidelberg; DE
Langue: Anglais
160,49 € (DE)
164,99 € (AT)
177,00 CHF (CH)
Available
XVI, 191 p. 39 illus., 32 illus. in color.

BB; Hardcover, Softcover / Medizin/Nichtklinische Fächer; Medizinische Chemie, Pharmazeutische Chemie; Verstehen; Post-translational Modifications; Proteasome; Ubiquitin; enzymes; therapy; Medical Biochemistry; Biomedical Research; Health Sciences; Medizinische Forschung; Medizin, allgemein; EA; BC

Crosstalk Between the SUMO and Ubiquitin Pathways.- A Tale of Two Giant Proteases.- Molecular Genetics of the Ubiquitin-Proteasome System: Lessons from Yeast.- Less Is More: How Protein Degradation Regulates Muscle Development.- Transcriptional Control and the Ubiquitin–Proteasome System.- Ubiquitination of Myc: Proteasomal Degradation and Beyond.- Regulation of Apoptosis and Cytokinesis by the Anti-apoptotic E2/E3 Ubiquitin-Ligase BRUCE.- Dissecting Roles of Ubiquitination in the p53 Pathway.- Regulation of T Cell Differentiation and Allergic Responses by the E3 Ubiquitin Ligase Itch.- Approaches to Discovering Drugs that Regulate E3 Ubiquitin Ligases.- Inhibiting Hdm2 and Ubiquitin-Activating Enzyme: Targeting the Ubiquitin Conjugating System in Cancer.
Latest findings in the field of ubiquitin and proteasome research Biochmemical, genetic and structural aspects are presented by top specialists to the field Includes supplementary material: sn.pub/extras

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