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2010

ISBN: 9783642098666

Springer, Taschenbuch, Auflage: Softcover reprint of hardcover 1st ed. 2009, 440 Seiten, Publiziert: 2010-11-22T00:00:01Z, Produktgruppe: Buch, Hersteller-Nr.: Illustrated, 1.48 kg, Pharm… Plus…

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Aquaporins (Handbook of Experimental Pharmacology, Band 190) - Livres de poche

2010, ISBN: 9783642098666

Springer, Taschenbuch, Auflage: Softcover reprint of hardcover 1st ed. 2009, 440 Seiten, Publiziert: 2010-11-22T00:00:01Z, Produktgruppe: Buch, Hersteller-Nr.: Illustrated, 1.48 kg, Pharm… Plus…

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Aquaporins - Livres de poche

2010, ISBN: 9783642098666

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Aquaporins by Eric Beitz Paperback | Indigo Chapters

The aquaporin field has matured at an exceptionally fast pace and we are at the verge to develop serious strategies to therapeutically modulate aquaporin function directly or via regulatory networks. Key prerequisites are available today: i. a considerable (and growing) number of aquaporin crystal structures for the rational design of inhibitory molecules, ii. elaborate molecular dynamics simulation techniques for theoretical analyses of selectivity mechanisms and docking experiments, iii. comprehensive data on aquaporin immunohistochemistry, iv. aquaporin knockout animals for physiological studies, and v. assay systems for compound library screenings. The structure of this volume on aquaporins follows the points laid out above and thus covers the developments from basic research to potential pharmacological use. Situated between pharmacology textbooks and recent scientific papers this book provides a timely overview for readers from the fundamental as well as the applied disciplines.

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EAN (ISBN-13): 9783642098666
ISBN (ISBN-10): 3642098665
Version reliée
Livre de poche
Date de parution: 2010
Editeur: Eric Beitz
440 Pages
Poids: 0,661 kg
Langue: eng/Englisch

Livre dans la base de données depuis 2011-06-12T07:20:55+02:00 (Zurich)
Page de détail modifiée en dernier sur 2022-11-09T00:40:19+01:00 (Zurich)
ISBN/EAN: 9783642098666

ISBN - Autres types d'écriture:
3-642-09866-5, 978-3-642-09866-6
Autres types d'écriture et termes associés:
Auteur du livre: beitz
Titre du livre: beitz, handbook


Données de l'éditeur

Auteur: Eric Beitz
Titre: Handbook of Experimental Pharmacology; Aquaporins
Editeur: Springer; Springer Berlin
424 Pages
Date de parution: 2010-11-22
Berlin; Heidelberg; DE
Imprimé / Fabriqué en
Langue: Anglais
320,99 € (DE)
329,99 € (AT)
354,00 CHF (CH)
POD
XVI, 424 p. 93 illus., 6 illus. in color.

BC; Hardcover, Softcover / Medizin/Pharmazie; Pharmakologie; Verstehen; aquaporin; brain; glycerol; kidney; physiology; water homeostasis; Pharmacology; Human Physiology; Life Sciences; Nephrology; Neurology; Hematology; Physiologie; Biowissenschaften, allgemein; Nierenheilkunde, Nephrologie; Neurologie und klinische Neurophysiologie; Hämatologie; BB

Aquaporin Protein Structure and Selectivity Mechanisms.- Discovery of the Aquaporins and Development of the Field.- The AQP Structure and Functional Implications.- Dynamics and Energetics of Permeation Through Aquaporins. What Do We Learn from Molecular Dynamics Simulations?.- In Vitro Analysis and Modification of Aquaporin Pore Selectivity.- Aquaporin Function in Mammalian Water Homeostasis.- Aquaporins in the Kidney.- Regulation of Aquaporin-2 Trafficking.- Role of Aquaporin-4 in Cerebral Edema and Stroke.- Aquaporins as Potential Drug Targets for Meniere's Disease and its Related Diseases.- Aquaporins in Secretory Glands and their Role in Sjögren's Syndrome.- Aquaporin Glycerol Permeability in Mammalian Physiology.- Skin Aquaporins: Function in Hydration, Wound Healing, and Skin Epidermis Homeostasis.- Function of Aquaporin-7 in the Kidney and the Male Reproductive System.- Role of Aquaporin-7 and Aquaporin-9 in Glycerol Metabolism; Involvement in Obesity.- New Members of Mammalian Aquaporins: AQP10–AQP12.- Aquaporin Functions Apart from Water and Glycerol Transport.- Structural Function of MIP/Aquaporin 0 in the Eye Lens; Genetic Defects Lead to Congenital Inherited Cataracts.- pH Regulated Anion Permeability of Aquaporin-6.- Aquaglyceroporins and Metalloid Transport: Implications in Human Diseases.- Ammonia and Urea Permeability of Mammalian Aquaporins.- Knock-Out Models Reveal New Aquaporin Functions.- Towards Therapeutic Use of Aquaporins.- Design, Synthesis and Assaying of Potential Aquaporin Inhibitors.- Aquaporin-1 Gene Transfer to Correct Radiation-Induced Salivary Hypofunction.
Includes supplementary material: sn.pub/extras

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