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Regulated turnover of extracellular matrix (ECM) is an important component of tissue homeostasis. In recent years, the enzymes that participate in, and control ECM turnover have b… Plus…

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2011, ISBN: 3642168604

2011 Gebundene Ausgabe Biochemie, Chemie / Biochemie, Eiweiß (chemisch), Protein, Biologie / Zellbiologie, Zellbiologie, Zelle (biologisch) / Zellbiologie, Zellbiologie (Zytologie), Col… Plus…

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Extracellular Matrix Degradation - edition reliée, livre de poche

2011, ISBN: 3642168604

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Détails sur le livre
Extracellular Matrix Degradation
Auteur:
Titre:
ISBN:

9783642168604


Regulated turnover of extracellular matrix (ECM) is an important component of tissue homeostasis. In recent years, the enzymes that participate in, and control ECM turnover have been the focus of research that touches on development, tissue remodeling, inflammation and disease. This volume in the Biology of Extracellular Matrix series provides a review of the known classes of proteases that degrade ECM both outside and inside the cell. The specific EMC proteases that are discussed include cathepsins, bacterial collagenases, matrix metalloproteinases, meprins, serine proteases, and elastases. The volume also discusses the domains responsible for specific biochemical characteristics of the proteases and the physical interactions that occur when the protease interacts with substrate. The topics covered in this volume provide an important context for understanding the role that matrix-degrading proteases play in normal tissue remodeling and in diseases such as cancer and lung disease.

Informations détaillées sur le livre - Extracellular Matrix Degradation


EAN (ISBN-13): 9783642168604
ISBN (ISBN-10): 3642168604
Version reliée
Date de parution: 2011
Editeur: Springer Berlin
255 Pages
Poids: 0,535 kg
Langue: eng/Englisch

Livre dans la base de données depuis 2008-07-05T19:53:57+02:00 (Zurich)
Page de détail modifiée en dernier sur 2023-08-19T23:52:50+02:00 (Zurich)
ISBN/EAN: 9783642168604

ISBN - Autres types d'écriture:
3-642-16860-4, 978-3-642-16860-4
Autres types d'écriture et termes associés:
Auteur du livre: robert park, parks
Titre du livre: the matrix, degradation, extracellular matrix

Données de l'éditeur

Auteur: William C. Parks; Robert Mecham
Titre: Biology of Extracellular Matrix; Extracellular Matrix Degradation
Editeur: Springer; Springer Berlin
255 Pages
Date de parution: 2011-04-09
Berlin; Heidelberg; DE
Imprimé / Fabriqué en
Langue: Anglais
160,49 € (DE)
164,99 € (AT)
177,00 CHF (CH)
POD
X, 255 p.

BB; Hardcover, Softcover / Biologie/Mikrobiologie; Zellbiologie (Zytologie); Verstehen; Collagen; Proteases; Proteoglycans; Proteolysis; Cell Biology; Biochemistry; Protein Biochemistry; Biomedical Research; Biochemie; Medizinische Forschung; BC

series provides a review of the known classes of proteases that degrade ECM both outside and inside the cell. The specific EMC proteases that are discussed include cathepsins, bacterial collagenases, matrix metalloproteinases, meprins, serine proteases, and elastases. The volume also discusses the domains responsible for specific biochemical characteristics of the proteases and the physical interactions that occur when the protease interacts with substrate. The topics covered in this volume provide an important context for understanding the role that matrix-degrading proteases play in normal tissue remodeling and in diseases such as cancer and lung disease.

Biology of Extracellular Matrix

Matrix Metalloproteinases and Their Inhibitors in Turnover and Degradation of Extracellular Matrix.- Role of Cysteine Cathepsins in Extracellular Proteolysis.- Cooperation between proteolysis and endocytosis in collagen turnover.- Pericellular Proteolysis.- Triple Helicase Activity and the Structural Basis of Collagenolysis.- Structural Basis of Extracellular Matrix Interactions with Matrix Metalloproteinases.- The Role of Matrix Metalloproteinases in Cellular Invasion and Metastasis.- Degradation of bone and the role of osteoclasts, bone lining cells and osteocytes.- Consequences of Elastolysis.

series provides a review of the known classes of proteases that degrade ECM both outside and inside the cell. The specific EMC proteases that are discussed include cathepsins, bacterial collagenases, matrix metalloproteinases, meprins, serine proteases, and elastases. The volume also discusses the domains responsible for specific biochemical characteristics of the proteases and the physical interactions that occur when the protease interacts with substrate. The topics covered in this volume provide an important context for understanding the role that matrix-degrading proteases play in normal tissue remodeling and in diseases such as cancer and lung disease.

is published in collaboration with the American Society for Matrix Biology.

Biology of Extracellular Matrix Biology of Extracellular Matrix
Provides timely reviews on current topics of ECM biology Improves our understanding of the role of matrix-degrading proteases in tissue remodeling and diseases The series is published in collaboration with the American Society for Matrix Biology Includes supplementary material: sn.pub/extras

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