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Optimized Response-Adaptive Clinical Trials: Sequential Treatment Allocation Based on Markov Decision Problems Thomas Ondra Author
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Two-armed response-adaptive clinical trials are modelled as Markov decision problems to pursue two overriding objectives: Firstly, to identify the superior treatment at the end of the… Plus…

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Optimized Response-Adaptive Clinical Trials - nouveau livre

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Two-armed response-adaptive clinical trials are modelled as Markov decision problems to pursue two overriding objectives: Firstly, to identify the superior treatment at the end of the tri… Plus…

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Optimized Response-Adaptive Clinical Trials - nouveau livre

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Two-armed response-adaptive clinical trials are modelled as Markov decision problems to pursue two overriding objectives: Firstly, to identify the superior treatment at the end of the tri… Plus…

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Optimized Response-Adaptive Clinical Trials: Sequential Treatment Allocation Based on Markov Decision Problems (BestMasters) - Livres de poche

2014, ISBN: 9783658083434

Springer Spektrum, Paperback, Auflage: 2015, 117 Seiten, Publiziert: 2014-12-18T00:00:01Z, Produktgruppe: Book, Hersteller-Nr.: 14 black & white illustrations, 2 black, 0.17 kg, Applied M… Plus…

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Optimized Response-Adaptive Clinical Trials: Sequential Treatment Allocation Based on Markov Decision Problems Thomas Ondra Author
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9783658083434

Informations détaillées sur le livre - Optimized Response-Adaptive Clinical Trials: Sequential Treatment Allocation Based on Markov Decision Problems Thomas Ondra Author


EAN (ISBN-13): 9783658083434
ISBN (ISBN-10): 3658083433
Version reliée
Livre de poche
Date de parution: 2015
Editeur: Springer Fachmedien Wiesbaden Core >1

Livre dans la base de données depuis 2014-12-26T17:14:45+01:00 (Zurich)
Page de détail modifiée en dernier sur 2023-12-05T02:30:15+01:00 (Zurich)
ISBN/EAN: 9783658083434

ISBN - Autres types d'écriture:
3-658-08343-3, 978-3-658-08343-4
Autres types d'écriture et termes associés:
Auteur du livre: ondra
Titre du livre: trial, adaptiv, clinical trials, markov

Données de l'éditeur

Auteur: Thomas Ondra
Titre: BestMasters; Optimized Response-Adaptive Clinical Trials - Sequential Treatment Allocation Based on Markov Decision Problems
Editeur: Springer Spektrum; Springer Fachmedien Wiesbaden GmbH
102 Pages
Date de parution: 2014-12-18
Wiesbaden; DE
Imprimé / Fabriqué en
Langue: Anglais
53,49 € (DE)
54,99 € (AT)
59,00 CHF (CH)
POD
XV, 102 p. 14 illus.

BC; Hardcover, Softcover / Mathematik/Wahrscheinlichkeitstheorie, Stochastik, Mathematische Statistik; Numerische Mathematik; Verstehen; Allocation Sequence; Backward Induction; Clinical Trial Designs; Policy Iteration; Value Iteration; Computational Mathematics and Numerical Analysis; Probability Theory; Analysis; Wahrscheinlichkeitsrechnung und Statistik; Stochastik; Mathematische Analysis, allgemein; EA

Two-armed response-adaptive clinical trials are modelled as Markov decision problems to pursue two overriding objectives: Firstly, to identify the superior treatment at the end of the trial and, secondly, to keep the number of patients receiving the inferior treatment small. Such clinical trial designs are very important, especially for rare diseases. Thomas Ondra presents the main solution techniques for Markov decision problems and provides a detailed description how to obtain optimal allocation sequences.ContentsIntroduction to Markov Decision Problems and ExamplesFinite and Infinite Horizon Markov Decision ProblemsSolution Algorithms: Backward Induction, Value Iteration and Policy IterationDesigning Response Adaptive Clinical Trials with Markov Decision ProblemsTarget GroupsResearchers and students in the fields of mathematics and statistics Professionals in the pharmaceutical industryPublication in the field of natural sciences Includes supplementary material: sn.pub/extras

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