[EAN: 9783844322071], Neubuch, [PU: LAP LAMBERT Academic Publishing], nach der Bestellung gedruckt Neuware - Printed after ordering - Breast cancer is the most common type of neoplasia in… Plus…
[EAN: 9783844322071], Neubuch, [PU: LAP LAMBERT Academic Publishing], nach der Bestellung gedruckt Neuware - Printed after ordering - Breast cancer is the most common type of neoplasia in women. Most of hereditary cases are associated with mutations of breast cancer-associated genes (BRCA). Preventive mastectomy and chemoprevention are the only approaches available so far to prevent the development of neoplasia in patients with specific genetic background. However, side effects and invasiveness of these procedures make necessary the development of alternative strategies. This book describes a novel approach to prevent breast cancer based on the restoration of BRCA1 functional gene into target cells using an engineered virus. In fact viruses have developed an efficient mechanism to deliver their genetic material into target cells; virus-derived vectors take advantages of this ability to vehiculate transgenes cells. To this aim a lentiviral vector expressing BRCA1 gene was produced. Restoration of gene function was validated in tumor and primary cells derived from patient encoding an inactive form of BRCA1, that, following gene delivery, restored the ability to repair DNA damages upon exposition to ionizing radiations These results pave the way to develop novel preventative approaches against human breast cancer. 80 pp. Englisch, Books<
[EAN: 9783844322071], Neubuch, [PU: LAP LAMBERT Academic Publishing Mrz 2011], This item is printed on demand - it takes 3-4 days longer - Neuware -Breast cancer is the most common type o… Plus…
[EAN: 9783844322071], Neubuch, [PU: LAP LAMBERT Academic Publishing Mrz 2011], This item is printed on demand - it takes 3-4 days longer - Neuware -Breast cancer is the most common type of neoplasia in women. Most of hereditary cases are associated with mutations of breast cancer-associated genes (BRCA). Preventive mastectomy and chemoprevention are the only approaches available so far to prevent the development of neoplasia in patients with specific genetic background. However, side effects and invasiveness of these procedures make necessary the development of alternative strategies. This book describes a novel approach to prevent breast cancer based on the restoration of BRCA1 functional gene into target cells using an engineered virus. In fact viruses have developed an efficient mechanism to deliver their genetic material into target cells; virus-derived vectors take advantages of this ability to vehiculate transgenes cells. To this aim a lentiviral vector expressing BRCA1 gene was produced. Restoration of gene function was validated in tumor and primary cells derived from patient encoding an inactive form of BRCA1, that, following gene delivery, restored the ability to repair DNA damages upon exposition to ionizing radiations These results pave the way to develop novel preventative approaches against human breast cancer. 80 pp. Englisch, Books<
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[EAN: 9783844322071], Neubuch, [PU: LAP LAMBERT Academic Publishing], MEDIZIN KLINISCHE FÄCHER VIRAL VECTOR GENE THERAPY BREAST CANCER, Dieser Artikel ist ein Print on Demand Artikel und … Plus…
[EAN: 9783844322071], Neubuch, [PU: LAP LAMBERT Academic Publishing], MEDIZIN KLINISCHE FÄCHER VIRAL VECTOR GENE THERAPY BREAST CANCER, Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Autor/Autorin: Vannucci LauraLaura Vannucci graduated in Biology in 2004 and received the Ph.D in Experimental and Molecular Oncology in 2009. Her Researches on gene therapy and vaccination were carried out with Prof. Mauro Pistello at Retrovirus ., Books<
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Softcover, PLEASE NOTE, WE DO NOT SHIP TO DENMARK. New Book. Shipped from UK in 4 to 14 days. Established seller since 2000. Please note we cannot offer an expedited shipping service from the UK., [PU: LAP Lambert Academic Publishing]<
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Softcover, New Book. Shipped from UK in 4 to 14 days. Established seller since 2000. Please note we cannot offer an expedited shipping service from the UK., [PU: LAP Lambert Academic Publishing]<
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[EAN: 9783844322071], Neubuch, [PU: LAP LAMBERT Academic Publishing], nach der Bestellung gedruckt Neuware - Printed after ordering - Breast cancer is the most common type of neoplasia in… Plus…
[EAN: 9783844322071], Neubuch, [PU: LAP LAMBERT Academic Publishing], nach der Bestellung gedruckt Neuware - Printed after ordering - Breast cancer is the most common type of neoplasia in women. Most of hereditary cases are associated with mutations of breast cancer-associated genes (BRCA). Preventive mastectomy and chemoprevention are the only approaches available so far to prevent the development of neoplasia in patients with specific genetic background. However, side effects and invasiveness of these procedures make necessary the development of alternative strategies. This book describes a novel approach to prevent breast cancer based on the restoration of BRCA1 functional gene into target cells using an engineered virus. In fact viruses have developed an efficient mechanism to deliver their genetic material into target cells; virus-derived vectors take advantages of this ability to vehiculate transgenes cells. To this aim a lentiviral vector expressing BRCA1 gene was produced. Restoration of gene function was validated in tumor and primary cells derived from patient encoding an inactive form of BRCA1, that, following gene delivery, restored the ability to repair DNA damages upon exposition to ionizing radiations These results pave the way to develop novel preventative approaches against human breast cancer. 80 pp. Englisch, Books<
[EAN: 9783844322071], Neubuch, [PU: LAP LAMBERT Academic Publishing Mrz 2011], This item is printed on demand - it takes 3-4 days longer - Neuware -Breast cancer is the most common type o… Plus…
[EAN: 9783844322071], Neubuch, [PU: LAP LAMBERT Academic Publishing Mrz 2011], This item is printed on demand - it takes 3-4 days longer - Neuware -Breast cancer is the most common type of neoplasia in women. Most of hereditary cases are associated with mutations of breast cancer-associated genes (BRCA). Preventive mastectomy and chemoprevention are the only approaches available so far to prevent the development of neoplasia in patients with specific genetic background. However, side effects and invasiveness of these procedures make necessary the development of alternative strategies. This book describes a novel approach to prevent breast cancer based on the restoration of BRCA1 functional gene into target cells using an engineered virus. In fact viruses have developed an efficient mechanism to deliver their genetic material into target cells; virus-derived vectors take advantages of this ability to vehiculate transgenes cells. To this aim a lentiviral vector expressing BRCA1 gene was produced. Restoration of gene function was validated in tumor and primary cells derived from patient encoding an inactive form of BRCA1, that, following gene delivery, restored the ability to repair DNA damages upon exposition to ionizing radiations These results pave the way to develop novel preventative approaches against human breast cancer. 80 pp. Englisch, Books<
NEW BOOK. Frais d'envoi EUR 9.90 BuchWeltWeit Inh. Ludwig Meier e.K., Bergisch Gladbach, Germany [57449362] [Rating: 5 (von 5)]
[EAN: 9783844322071], Neubuch, [PU: LAP LAMBERT Academic Publishing], MEDIZIN KLINISCHE FÄCHER VIRAL VECTOR GENE THERAPY BREAST CANCER, Dieser Artikel ist ein Print on Demand Artikel und … Plus…
[EAN: 9783844322071], Neubuch, [PU: LAP LAMBERT Academic Publishing], MEDIZIN KLINISCHE FÄCHER VIRAL VECTOR GENE THERAPY BREAST CANCER, Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Autor/Autorin: Vannucci LauraLaura Vannucci graduated in Biology in 2004 and received the Ph.D in Experimental and Molecular Oncology in 2009. Her Researches on gene therapy and vaccination were carried out with Prof. Mauro Pistello at Retrovirus ., Books<
Softcover, PLEASE NOTE, WE DO NOT SHIP TO DENMARK. New Book. Shipped from UK in 4 to 14 days. Established seller since 2000. Please note we cannot offer an expedited shipping service from… Plus…
Softcover, PLEASE NOTE, WE DO NOT SHIP TO DENMARK. New Book. Shipped from UK in 4 to 14 days. Established seller since 2000. Please note we cannot offer an expedited shipping service from the UK., [PU: LAP Lambert Academic Publishing]<
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Softcover, New Book. Shipped from UK in 4 to 14 days. Established seller since 2000. Please note we cannot offer an expedited shipping service from the UK., [PU: LAP Lambert Academic Publ… Plus…
Softcover, New Book. Shipped from UK in 4 to 14 days. Established seller since 2000. Please note we cannot offer an expedited shipping service from the UK., [PU: LAP Lambert Academic Publishing]<
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Breast cancer is the most common type of neoplasia in women. Most of hereditary cases are associated with mutations of breast cancer-associated genes (BRCA). Preventive mastectomy and chemoprevention are the only approaches available so far to prevent the development of neoplasia in patients with specific genetic background. However, side effects and invasiveness of these procedures make necessary the development of alternative strategies. This book describes a novel approach to prevent breast cancer based on the restoration of BRCA1 functional gene into target cells using an engineered virus. In fact viruses have developed an efficient mechanism to deliver their genetic material into target cells; virus-derived vectors take advantages of this ability to vehiculate transgenes cells. To this aim a lentiviral vector expressing BRCA1 gene was produced. Restoration of gene function was validated in tumor and primary cells derived from patient encoding an inactive form of BRCA1, that, following gene delivery, restored the ability to repair DNA damages upon exposition to ionizing radiations These results pave the way to develop novel preventative approaches against human breast cancer.
Informations détaillées sur le livre - Gene therapy for breast cancer treatment: Engineered viruses: to turn the bad into the good
EAN (ISBN-13): 9783844322071 ISBN (ISBN-10): 3844322078 Version reliée Livre de poche Date de parution: 2011 Editeur: LAP LAMBERT Academic Publishing
Livre dans la base de données depuis 2007-09-26T21:46:40+02:00 (Zurich) Page de détail modifiée en dernier sur 2023-10-08T09:53:12+02:00 (Zurich) ISBN/EAN: 9783844322071
ISBN - Autres types d'écriture: 3-8443-2207-8, 978-3-8443-2207-1 Autres types d'écriture et termes associés: Auteur du livre: vannucci Titre du livre: the treatment, therapy, cancer, the gene
