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Clinical Pharmacokinetics, A Short Introduction - Devarakonda R. Krishna, Ulrich Klotz

(*)

Devarakonda R. Krishna, Ulrich Klotz:
Clinical Pharmacokinetics, A Short Introduction - nouveau livre

ISBN: 9783540524588

The first part of this book enables the reader to be familiarized with basic concepts of pharmacokinetics (Absorption, Distribution, Metabolism and Excretion - ADM E) following single dos… Plus…

The first part of this book enables the reader to be familiarized with basic concepts of pharmacokinetics (Absorption, Distribution, Metabolism and Excretion - ADM E) following single dose administration. In this part these principles are applied to clinically relevant situations, namely, multiple or (sub) chronic administration. In day to day practice besides acute drug response, often a longer duration of action is desired. This situation needs the under standing of changes in pharmacokinetics of drugs upon repeated administra tion, and the dosage regimen has to be accordingly adjusted for achieving uniform therapeutic levels for desired period of time. 2 Multiple dosing The basic mathematical relationships applicable to single dose administration kinetics are also valid (with slight modifications) for multiple dose kinetics. In multiple dose therapy the ultimate purpose is to achieve a steady drug effect or response with minimum side effects. As mentioned before, this can be achieved in most cases by maintaining the plasma concentrations in therapeutic range for required number of hours or days. This may be considered as a general rule with an exception of nitrates, in which case the concentrations during the interval between two doses (called "dosing interval") should fall below a critical threshold level, such that tolerance does not develop. A drug is commonly administered in fixed doses at constant intervals of time so that the amount lost through elimination is replaced after each dose. The first part of this book enables the reader to be familiarized with basic concepts of pharmacokinetics (Absorption, Distribution, Metabolism and Excretion - ADM E) following single dose administration. In this part these principles are applied to clinically relevant situations, namely, multiple or (sub) chronic administration. In day to day practice besides acute drug response, often a longer duration of action is desired. This situation needs the under standing of changes in pharmacokinetics of drugs upon repeated administra tion, and the dosage regimen has to be accordingly adjusted for achieving uniform therapeutic levels for desired period of time. 2 Multiple dosing The basic mathematical relationships applicable to single dose administration kinetics are also valid (with slight modifications) for multiple dose kinetics. In multiple dose therapy the ultimate purpose is to achieve a steady drug effect or response with minimum side effects. As mentioned before, this can be achieved in most cases by maintaining the plasma concentrations in therapeutic range for required number of hours or days. This may be considered as a general rule with an exception of nitrates, in which case the concentrations during the interval between two doses (called "dosing interval") should fall below a critical threshold level, such that tolerance does not develop. A drug is commonly administered in fixed doses at constant intervals of time so that the amount lost through elimination is replaced after each dose. Inhoud: Taal: Engels; Bindwijze: Paperback; Druk: Softcover reprint of the original 1st ed. 1990; Verschijningsdatum: juli 1990; Aantal pagina's: 149 pagina's; Illustraties: Nee; Betrokkenen: Auteur(s): Devarakonda R. Krishna | Ulrich Klotz | D. R. Krishna; Uitgever: Springer-Verlag Berlin and Heidelberg GmbH & Co. KG; EAN: Overige kenmerken: Extra groot lettertype: Nee; Gewicht: 280 g; Verpakking breedte: 155 mm; Verpakking hoogte: 0 mm; Verpakking lengte: 235 mm; Engels | Druk: Softcover reprint of the original 1st ed. 1990 | Paperback | 9783540524588 | 149 pagina's, Boeken, Geneeskunde & Verpleging, Specialistische geneeskunde, Farmacologie, Klinische & Interne geneeskunde, Springer-Verlag Berlin and Heidelberg GmbH & Co. KG<

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Clinical Pharmacokinetics A Short Introduction - Klotz, Ulrich; Krishna, Devarakonda R.

(*)

Klotz, Ulrich; Krishna, Devarakonda R.:
Clinical Pharmacokinetics A Short Introduction - Livres de poche

1990, ISBN: 3540524584

Softcover reprint of the original 1st ed. 1990 Kartoniert / Broschiert Klinische und Innere Medizin, Arzneimittelbehandlung; Arzneimittelevaluierung; Dosierungsberechnungen; Pharmakokin… Plus…

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Clinical Pharmacokinetics A Short Introduction - Klotz, Ulrich; Krishna, Devarakonda R.

(*)

Klotz, Ulrich; Krishna, Devarakonda R.:
Clinical Pharmacokinetics A Short Introduction - Livres de poche

1990, ISBN: 3540524584

Softcover reprint of the original 1st ed. 1990 Kartoniert / Broschiert Klinische und Innere Medizin, Arzneimittelbehandlung; Arzneimittelevaluierung; Dosierungsberechnungen; Pharmakokin… Plus…

Achtung-Buecher.de

MARZIES.de Buch- und Medienhandel, 14621 Schönwalde-Glien
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Details...

(*) Livre non disponible signifie que le livre est actuellement pas disponible à l'une des plates-formes associées nous recherche.

Clinical Pharmacokinetics - Devarakonda R. Krishna

(*)

Devarakonda R. Krishna:
Clinical Pharmacokinetics - Livres de poche

ISBN: 9783540524588

Paperback, [PU: Springer-Verlag Berlin and Heidelberg GmbH & Co. KG], 2 Multiple dosing The basic mathematical relationships applicable to single dose administration kinetics are also val… Plus…

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Clinical Pharmacokinetics - Devarakonda R. Krishna; Ulrich Klotz

(*)

Devarakonda R. Krishna; Ulrich Klotz:
Clinical Pharmacokinetics - Livres de poche

1990, ISBN: 9783540524588

A Short Introduction, Buch, Softcover, Softcover reprint of the original 1st ed. 1990, [PU: Springer Berlin], Springer Berlin, 1990

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Clinical Pharmacokinetics, A Short Introduction - Devarakonda R. Krishna, Ulrich Klotz

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Devarakonda R. Krishna, Ulrich Klotz:

Clinical Pharmacokinetics, A Short Introduction - nouveau livre

ISBN: 9783540524588

The first part of this book enables the reader to be familiarized with basic concepts of pharmacokinetics (Absorption, Distribution, Metabolism and Excretion - ADM E) following single dos… Plus…

The first part of this book enables the reader to be familiarized with basic concepts of pharmacokinetics (Absorption, Distribution, Metabolism and Excretion - ADM E) following single dose administration. In this part these principles are applied to clinically relevant situations, namely, multiple or (sub) chronic administration. In day to day practice besides acute drug response, often a longer duration of action is desired. This situation needs the under standing of changes in pharmacokinetics of drugs upon repeated administra tion, and the dosage regimen has to be accordingly adjusted for achieving uniform therapeutic levels for desired period of time. 2 Multiple dosing The basic mathematical relationships applicable to single dose administration kinetics are also valid (with slight modifications) for multiple dose kinetics. In multiple dose therapy the ultimate purpose is to achieve a steady drug effect or response with minimum side effects. As mentioned before, this can be achieved in most cases by maintaining the plasma concentrations in therapeutic range for required number of hours or days. This may be considered as a general rule with an exception of nitrates, in which case the concentrations during the interval between two doses (called "dosing interval") should fall below a critical threshold level, such that tolerance does not develop. A drug is commonly administered in fixed doses at constant intervals of time so that the amount lost through elimination is replaced after each dose. The first part of this book enables the reader to be familiarized with basic concepts of pharmacokinetics (Absorption, Distribution, Metabolism and Excretion - ADM E) following single dose administration. In this part these principles are applied to clinically relevant situations, namely, multiple or (sub) chronic administration. In day to day practice besides acute drug response, often a longer duration of action is desired. This situation needs the under standing of changes in pharmacokinetics of drugs upon repeated administra tion, and the dosage regimen has to be accordingly adjusted for achieving uniform therapeutic levels for desired period of time. 2 Multiple dosing The basic mathematical relationships applicable to single dose administration kinetics are also valid (with slight modifications) for multiple dose kinetics. In multiple dose therapy the ultimate purpose is to achieve a steady drug effect or response with minimum side effects. As mentioned before, this can be achieved in most cases by maintaining the plasma concentrations in therapeutic range for required number of hours or days. This may be considered as a general rule with an exception of nitrates, in which case the concentrations during the interval between two doses (called "dosing interval") should fall below a critical threshold level, such that tolerance does not develop. A drug is commonly administered in fixed doses at constant intervals of time so that the amount lost through elimination is replaced after each dose. Inhoud: Taal: Engels; Bindwijze: Paperback; Druk: Softcover reprint of the original 1st ed. 1990; Verschijningsdatum: juli 1990; Aantal pagina's: 149 pagina's; Illustraties: Nee; Betrokkenen: Auteur(s): Devarakonda R. Krishna | Ulrich Klotz | D. R. Krishna; Uitgever: Springer-Verlag Berlin and Heidelberg GmbH & Co. KG; EAN: Overige kenmerken: Extra groot lettertype: Nee; Gewicht: 280 g; Verpakking breedte: 155 mm; Verpakking hoogte: 0 mm; Verpakking lengte: 235 mm; Engels | Druk: Softcover reprint of the original 1st ed. 1990 | Paperback | 9783540524588 | 149 pagina's, Boeken, Geneeskunde & Verpleging, Specialistische geneeskunde, Farmacologie, Klinische & Interne geneeskunde, Springer-Verlag Berlin and Heidelberg GmbH & Co. KG<

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Clinical Pharmacokinetics A Short Introduction - Klotz, Ulrich; Krishna, Devarakonda R.

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Klotz, Ulrich; Krishna, Devarakonda R.:

Clinical Pharmacokinetics A Short Introduction - Livres de poche

1990, ISBN: 3540524584

Softcover reprint of the original 1st ed. 1990 Kartoniert / Broschiert Klinische und Innere Medizin, Arzneimittelbehandlung; Arzneimittelevaluierung; Dosierungsberechnungen; Pharmakokin… Plus…

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Clinical Pharmacokinetics A Short Introduction - Klotz, Ulrich; Krishna, Devarakonda R.

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Klotz, Ulrich; Krishna, Devarakonda R.:
Clinical Pharmacokinetics A Short Introduction - Livres de poche

1990

ISBN: 3540524584

Softcover reprint of the original 1st ed. 1990 Kartoniert / Broschiert Klinische und Innere Medizin, Arzneimittelbehandlung; Arzneimittelevaluierung; Dosierungsberechnungen; Pharmakokin… Plus…

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Clinical Pharmacokinetics - Devarakonda R. Krishna

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Devarakonda R. Krishna:
Clinical Pharmacokinetics - Livres de poche

ISBN: 9783540524588

Paperback, [PU: Springer-Verlag Berlin and Heidelberg GmbH & Co. KG], 2 Multiple dosing The basic mathematical relationships applicable to single dose administration kinetics are also val… Plus…

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Clinical Pharmacokinetics - Devarakonda R. Krishna; Ulrich Klotz

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Devarakonda R. Krishna; Ulrich Klotz:
Clinical Pharmacokinetics - Livres de poche

1990, ISBN: 9783540524588

A Short Introduction, Buch, Softcover, Softcover reprint of the original 1st ed. 1990, [PU: Springer Berlin], Springer Berlin, 1990

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Détails sur le livre

Clinical Pharmacokinetics

Auteur:	Devarakonda R. Krishna
Titre:	Clinical Pharmacokinetics
ISBN:	9783540524588

This basic introduction to pharmacokinetics is designed specifically for the young medical doctor. The text keeps the role of mathematical derivations to a minimum and brings the clinical importance of pharmacokinetics upstage. The first section of the book presents the basic principles of drug disposition, from absorption and distribution to elimination. Model problems and their solutions are presented in every chapter, and patho-physiological factors are also taken into consideration. The second section shows clinical applications, and how drug treatment and evaluation can be made more effective. The third section touches upon international nomenclature and includes numerous tables which can serve as quick and useful guidelines in clinical practice.

Informations détaillées sur le livre - Clinical Pharmacokinetics

EAN (ISBN-13): 9783540524588
ISBN (ISBN-10): 3540524584
Version reliée
Livre de poche
Date de parution: 1990
Editeur: Springer Berlin

Livre dans la base de données depuis 2008-02-25T23:44:47+01:00 (Zurich)
Page de détail modifiée en dernier sur 2023-07-07T12:24:49+02:00 (Zurich)
ISBN/EAN: 9783540524588

ISBN - Autres types d'écriture:
3-540-52458-4, 978-3-540-52458-8
Autres types d'écriture et termes associés:
Auteur du livre: klotz, krishna
Titre du livre: clinical pharmacokinetics

Données de l'éditeur

Auteur: Devarakonda R. Krishna; Ulrich Klotz
Titre: Clinical Pharmacokinetics - A Short Introduction
Editeur: Springer; Springer Berlin
149 Pages
Date de parution: 1990-07-31
Berlin; Heidelberg; DE
Langue: Anglais
53,49 € (DE)
54,99 € (AT)
59,00 CHF (CH)
Available
VI, 149 p.

BC; Hardcover, Softcover / Medizin/Klinische Fächer; Klinische und Innere Medizin; Verstehen; Arzneimittelbehandlung; Arzneimittelevaluierung; Dosierungsberechnungen; Pharmakokinetik; Internal Medicine; Pharmacology; Pharmakologie; EA

I: Basic pharmacokinetics.- Historical note.- 1 Introduction and definitions.- 2 Absorption.- 3 Distribution.- 4 Elimination.- II: Pharmacokinetic principles and their clinical significance.- 1 Introduction.- 2 Multiple dosing.- 3 Drug interactions.- 4 Concentration — effect relationships.- III: Appendix.- 1 Recommended pharmacokinetic symbols, definitions and dimensions.- 2 Glossary.- 3 Tables with pharmacokinetic data.

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9780387524580 Clinical Pharmacokinetics: A Short Introduction (D. R. Krishna; U. Klotz)

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